By default, without any input on your part, CrashPlan will be configured to back up any user profile of anyone who logs on to your computer (C:\Users\ for PCs or /Users/ for Macs). This will also back up any files and folders at the root of your hard disk that are not operating system or program/application files. This setup should work appropriately for the majority of users without any further modification. If you would prefer to change what is backed up, you have that ability. This article explains how to configure your Crashplan Backup from the standard method.
Instructions
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Open the CrashPlan application by clicking on the icon in your system tray (Windows), or in the status bar (Mac). Select "Open CrashPlan" or "Show Application."

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The CrashPlan application will open and display the Welcome screen. Click on the Manage Files button.

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Navigate to the drive, folder, or files that you want to add or remove.
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Deselect the check box next to any item you want to delete from your backup.Select an empty box to add an item to your backup. A minus sign indicates that a subfolder within this folder is selected for backup. New subfolders within the folder will not be automatically added to your backup file selection. A check mark indicates that this folder is selected for backup. New subfolders within the folder will be automatically added to your backup file selection.

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Click Save. If you deselected any files or folders, the Delete Files from Backup warning displays.
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If applicable, select I understand to confirm you want to delete deselected files from your backup.
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If applicable, select Delete. After changing the file selection, the CrashPlan app synchronizes the files selected for backup with the files already backed up to that destination.

More information
Please reach out to the Help Desk for any further questions or concerns.